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Currently, GREAT supports recent assemblies of the well-annotated human (UCSC hg38 and UCSC hg19), and mouse (UCSC mm10 and UCSC mm9). The previous assembly versions of human and mouse genomes as well as zebrafish (UCSC danRer7) genome are is supported in the previous versions of GREAT. Please check Genes pages for the list of genes included in the GREAT analysis in each genome assemby.
Can I use a different species or assembly?
If you have genomic regions defined for a different species or assembly from the ones we currently support, you can use the UCSC LiftOver utility to convert to a supported assembly. The LiftOver typically works very well for within-species coordinate conversion (e.g. from one human assembly to another), but it can also be used as a the best approximation of mapping regions in one genome to the orthologous regions of a genome for a different species (e.g., from chimpanzee to human), although more caution is obviously advised in these cases.
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- A decent genome assembly.
- A decent reference gene set.
- Gene annotations. Typically in the form of an ontology , and gene to ontology term mappings.
- A user community for said species.
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