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Description

The MSigDB Perturbation ontology contains gene sets that represent gene expression signatures of genetic and chemical perturbations. A number of these gene sets come in pairs: an xxx_UP (xxx_DN)

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gene

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set

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representing

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genes

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induced

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(repressed)

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by

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the

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perturbation.

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Statistics

The human hg19 ontology contains 2,374

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gene

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sets,

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16,150

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genes,

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and

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238,746

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associations.

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The

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human

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hg18

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ontology

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contains

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2,374

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gene

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sets,

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16,153

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genes,

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and

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238,720

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associations.

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The

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mouse

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mm9

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ontology

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contains

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2,373

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gene

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sets,

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14,631

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genes,

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and

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221,705

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associations.

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Download

All data for this ontology was downloaded on September 30, 2010 (MSigDB version 3.0).

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GREAT

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v1.2

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GREAT

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v1.2

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MSigDB

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Perturbation

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statistics

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are

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available

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here

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.

References