GREAT v1.8 Ontologies
Gene Ontology (GO)
Phenotype Data and Human Disease
Mouse Phenotype v1.8 - data about mouse genotype - phenotype associations mapped to human genes
Human Phenotype v1.8 - data of human phenotypes mapped to human genes
Disease Ontology v1.8 - data linking human diseases to associated genes
MSigDB Cancer Neighborhood v1.8 - gene sets defined by correlated expression profiles with cancer-associated genes
Zebrafish Phenotype v1.8 - data about zebrafish genotype - phenotype associations primarily obtained by curators from the literature
Pathway Data
PANTHER Pathway v1.8 - primarily signaling pathways
Pathway Commons v1.8 - a collection of pathways from multiple sources
BioCyc Pathway v1.8 - metabolic pathways
MSigDB Pathway v1.8 - gene sets from pathway databases
Wiki Pathways v1.8 - zebrafish pathway data
Gene Expression
MGI Expression Detected v1.8 - genes detected as expressed in data with a focus on gene expression during mouse development
MSigDB Perturbation v1.8 - gene sets that change their expression after genetic and chemical perturbations
Zebrafish Wildtype Expression v1.8 - genes detected as expressed in wildtype zebrafish during development
Regulatory Motifs
Transcription Factor Targets v1.8 - genes identified by a transcription factor ChIP-chip experiment
MSigDB Predicted Promoter Motifs v1.8 - gene sets that share a transcription factor binding motif
MSigDB miRNA Motifs v1.8 - gene sets that share a 3'-UTR microRNA binding motif
miRNA Targets v1.8 - genes that are downregulated in a microRNA overexpression experiment
Gene Families
InterPro v1.8 - protein domains, families and functional sites
TreeFam v1.8 - gene families of paralogs
HGNC Gene Families v1.8 - gene sets based on sequence similarity, data from the literature, and manual curation