Policy

See our versioning policy here.

2.0

April 3, 2012

• Mouse and human ontology data has been updated with new data so reproducing results prior to 2.0 need to be done using 1.8
• Extended programming interface to allow batch jobs to receive tsv output
• Added the export "All data as .tsv" option to "Global Export".
• The export for individual ontologies was also extended to output gene and regions hit and the FDR values.
• Added data visualization features to GREAT
  • Export tables as barplots
  • View enriched terms in hierarchy
• New modern CSS skin
• Zebrafish ontology data remains identical to GREAT 1.8 and thus can be reproduced using the 2.0 interface

1.8

May 31, 2011

• Added genomic region/gene association graphs to main results page.
• Enhanced the term details page to:
  • Include term-specific graphs,
  • Link specifically between genomic regions and genes, and
  • Open UCSC genome browser shots at a gene's regulatory domain.
• Added informative error messages when an input BED file has errors.
• All previously-existing ontology data remain identical to GREAT 1.5, 1.6, and 1.7, so reproducing GREAT 1.5, 1.6, or 1.7 runs happens automatically in 1.8.

1.7

March 29, 2011

• Added support for two phenotype ontologies (Human Phenotype and Osborne Annotated Disease Ontology) in the human and mouse assemblies.
• All previously-existing ontology data remain identical to GREAT 1.5 and 1.6, so reproducing GREAT 1.5 and 1.6 runs happens automatically in 1.7.

1.6

Jan 27, 2011

• Added support for the zebrafish Zv9 (UCSC danRer7, Jul/2010) assembly.
• All human- and mouse-related data remain identical to GREAT 1.5, so reproducing GREAT 1.5 runs happens automatically in 1.6.

1.5

Nov 19, 2010

• Added ability to download mapping between input regions and genes.
• Added support for the human GRCh37 (UCSC hg19, Feb/2009) assembly.
• Updated all ontologies from original data sources.
• Added filtering and display options to both whole genome and foreground/background tests.
• Enabled programmatic access to foreground/background test.
• Enabled submission of compressed data.
• Enabled submission of larger datasets.
• Slightly modified the basal+extension regulatory domain calculation logic.
• Created a versioning system for exact reproduction of analyses performed on any earlier date.

1.2

May 2, 2010

• First public release, coinciding with Nature Biotechnology paper publication.
• Supports the human NCBI build 36.1 (UCSC hg18, Mar/2006) and mouse NCBI build 37 (UCSC mm9, Jul/2007) genome assemblies.

1.0.0

Apr 27, 2009

• First internal release.